Diaphragm dysfunction during weaning from mechanical ventilation: an underestimated phenomenon with clinical implications
نویسندگان
چکیده
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2018. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2018 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901 .
منابع مشابه
Effects of mechanical ventilation on diaphragm function and biology.
The pathophysiological mechanisms of weaning from mechanical ventilation are not fully known, but there is accumulating evidence that mechanical ventilation induces inspiratory muscle dysfunction. Recently, several animal models have provided potential mechanisms for mechanical ventilation-induced effects on muscle function. In patients, weaning difficulties are associated with inspiratory musc...
متن کاملMechanical ventilation, diaphragm weakness and weaning: a rehabilitation perspective.
Most patients are easily liberated from mechanical ventilation (MV) following resolution of respiratory failure and a successful trial of spontaneous breathing, but about 25% of patients experience difficult weaning. MV use leads to cellular changes and weakness, which has been linked to weaning difficulties and has been labeled ventilator induced diaphragm dysfunction (VIDD). Aggravating facto...
متن کاملCritical illness and mechanical ventilation: effects on the diaphragm.
Although life-saving, mechanical ventilation is associated with numerous complications. These include pneumonia, cardiovascular compromise, barotrauma, and ventilator-induced lung injury. Recent data from animal studies suggest that controlled mechanical ventilation can cause dysfunction of the diaphragm, decreasing its force-generating capacity--a condition referred to as ventilator-induced di...
متن کاملInfluence of weaning methods on the diaphragm after mechanical ventilation in a rat model
BACKGROUND Mechanical ventilation (MV) is associated with diaphragm weakness, a phenomenon termed ventilator-induced diaphragmatic dysfunction. Weaning should balance diaphragmatic loading as well as prevention of overload after MV. The weaning methods pressure support ventilation (PSV) and spontaneous breathing trials (SBT) lead to gradual or intermittent reloading of a weak diaphragm, respect...
متن کاملThe critical illness polyneuropathy in septic patients with prolonged weaning from mechanical ventilation: is the diaphragm also affected? A pilot study.
BACKGROUND Critical illness myopathy and/or neuropathy (CRIMYNE) is a common alteration seen in the ICU. The currently available bedside methods of measuring respiratory and peripheral muscle function in critically ill patients are somewhat inadequate. The objective of this study was to evaluate the presence of diaphragmatic and peripheral CRIMYNE in septic patients with prolonged weaning from...
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عنوان ژورنال:
دوره 22 شماره
صفحات -
تاریخ انتشار 2018